AzoLPA

简要描述：AzoLPA as an extracellular signaling molecule and activates LPA1-6 receptors.

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Description:Lysophosphatidic acid (LPA) acts as an extracellular signaling molecule and activates LPA1-6 receptors. These receptors are of particular importance in the nervous, cardiovascular, reproductive, gastrointestinal, and pulmonary systems. AzoLPA is embedded with an azobenzene photoswitch which enables the optical control of LPA receptor activation. The light-induced cis- form shows greater activation of LPA receptors than its dark-adapted trans- form.

Name: AzoLPACAS#: 2389048-52-4Chemical Formula: C23H34N3O7PExact Mass: 495.2134Molecular Weight: 495.51Elemental Analysis: C, 55.75; H, 6.92; N, 8.48; O, 22.60; P, 6.25

Synonym:AzoLPA; 1-(E)-4-(4-((4-butylphenyl)diazenyl)phenyl)butanoyl]-2-hydroxy-sn-glycero-3-phosphate (ammonium salt)

IUPAC/Chemical Name:ammonium (R,E)-3-((4-(4-((4-butylphenyl)diazenyl)phenyl)butanoyl)oxy)-2-hydroxypropyl hydrogen phosphate

SMILES Code:OP(OC[C@]([H])(O)COC(CCCC1=CC=C(/N=N/C2=CC=C(CCCC)C=C2)C=C1)=O)([O-])=O.[NH4+]

Appearance:Solid powder

Purity:>98% (or refer to the Certificate of Analysis)

Shipping Condition:Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:Soluble in DMSO

Shelf Life:>3 years if stored properly

Drug Formulation:This drug may be formulated in DMSO

Stock Solution Storage:0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:2934.99.9001

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