AY77

简要描述：AY77 is a Potent protease activated receptor 2 (PAR2) calcium-biased agonist (EC50 40 nM, Ca2+; EC50 2 µM, ERK1/2).

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Description:AY77 is a Potent protease activated receptor 2 (PAR2) calcium-biased agonist (EC50 40 nM, Ca2+; EC50 2 µM, ERK1/2).

Name: AY77CAS#: 1835734-92-3Chemical Formula: C21H32N4O4Exact Mass: 404.2424Molecular Weight: 404.511Elemental Analysis: C, 62.35; H, 7.97; N, 13.85; O, 15.82

Synonym:AY77; AY 77; AY-77; Isox-Cha-Chg-NH2;

IUPAC/Chemical Name:N-((S)-1-(((S)-2-amino-1-cyclohexyl-2-oxoethyl)amino)-3-cyclohexyl-1-oxopropan-2-yl)isoxazole-5-carboxamide

InChi Key:CAYJNBJPGBBDAS-WMZOPIPTSA-N

InChi Code:InChI=1S/C21H32N4O4/c22-19(26)18(15-9-5-2-6-10-15)25-20(27)16(13-14-7-3-1-4-8-14)24-21(28)17-11-12-23-29-17/h11-12,14-16,18H,1-10,13H2,(H2,22,26)(H,24,28)(H,25,27)/t16-,18-/m0/s1

SMILES Code:O=C(C1=CC=NO1)N[C@@H](CC2CCCCC2)C(N[C@@H](C3CCCCC3)C(N)=O)=O

Appearance:Solid powder

Purity:>98% (or refer to the Certificate of Analysis)

Shipping Condition:Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition:Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility:Soluble in DMSO

Shelf Life:>2 years if stored properly

Drug Formulation:This drug may be formulated in DMSO

Stock Solution Storage:0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code:2934.99.9001

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