RD TOCRIS一级代理，Z-Guggulsterone供应CAS号39025-23-5

产品型号：3570

金山科研平台授权一级代理，产品询价请咨询微信：jinshanbio

RD TOCRIS一级代理，Z-Guggulsterone供应CAS号39025-23-5我公司代理RD产品和tocris产品Z-Guggulsterone货号：3570规格：10mg，50mg

金山科研平台授权代理，咨询微信：jinshanbio

RD TOCRIS一级代理，Z-Guggulsterone供应CAS号39025-23-5

Catalog Number:3570

Chemical Name:(Z)-Pregna-4,17(20)-diene-3,16-dione

详细产品信息：

Biological ActivityBroad spectrum steroid receptor ligand; mineralocorticoid, progesterone and glucocorticoid receptor antagonist (Kivalues are 37, 224 and 252 nM respectively) and weak androgen receptor agonist (Ki= 315 nM). Induces apoptosis in prostate cancer cells and inhibits angiogenesis via suppression of the VEGF-VEGFR2-Akt signaling pathway. Exhibits antilipidemic activity via antagonism of the farnesoid X receptor (FXR) and displays antiseptic, antirheumatic and anti-inflammatory activityin vivo. More active isomer ofguggulsterone(Cat. No. 2013).

Technical Data

M.Wt:

312.45

Formula:

C21H28O2

Solubility:

Soluble to 20 mM in DMSO with gentle warming and to 10 mM in ethanol with gentle warming

Purity:

>98%

Storage:

Store at RT

CAS No:

39025-23-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.